Chemical safety technical specification


Part I Chemical and enterprise identification


Chinese name of chemical: trifluoroacetic anhydride


Chemical name: Trifluoroacetic anhydride


Recommended use: pharmaceutical, pesticide intermediates


Limited use of the product: It shall not be used as a food additive


The second part is danger summary


Physical and chemical hazards: inhalation, ingestion, transdermal absorption. This product is flammable, corrosive and strong


It can cause burns to the human body.


Health hazard: corrosive. Strong irritation to the eyes, skin, mucous membranes and upper respiratory tract


Yes. Inhalation can cause laryngeal, bronchospasm, chemical pneumonia, pulmonary edema. Contact can cause


Burning sensation, cough, headache, vomiting, etc.


Environmental hazard: The substance is hazardous to the environment.


GHS risk category: According to the General Rules for the Classification and Risk Disclosure of Chemicals (GB13690-2009)


And chemical classification, warning label and warning description specification series standards, the product is rotten


Fluid erosion, skin corrosion/irritation, severe eye damage/eye irritation, respiratory or skin irritation


Min.


Hazard information: Corrosion.


Precautions:


Precautions: Do not contact spills directly. Cut off the source of leakage as much as possible. Away from the fire,


Heat source. Explosion-proof lighting and ventilation facilities are adopted. Wear rubber gloves, protective glasses, and protective face


Cover, wear a tape vest. After work, shower and change clothes. Smoking and eating are prohibited on site


And drinking water. Do not release into the environment.


Accident response: Quickly evacuate the contaminated area to the safety zone, and isolation, strict


Restrict access. Cut off the fire. Skin contact: Remove contaminated clothing, rinse skin thoroughly,


Hair, nails, etc. Seek medical attention. Eye contact: Lift eyelids and rinse eyes. Seek medical attention. Inhalation:


Quickly remove from scene to fresh air. Keep your airway clear. Seek medical attention. Ingestion: Gargle.


Seek medical attention. Collect the spill. Use dry powder and sand in case of fire.


Safe storage: Store in a cool, ventilated warehouse. Keep away from fire and heat. antiyang


The light is direct. The storage temperature should not exceed 40℃. Keep the container sealed. Should be associated with oxidants, acids,


Alkalis and edible chemicals should be stored separately, and mixed storage should be avoided. Explosion-proof lighting and ventilation are adopted


Grant. Do not use mechanical equipment and tools that are prone to spark. The storage area should have a leak emergency


Handling equipment and suitable containment materials.


Disposal of waste: disposal in accordance with the requirements of relevant national and local regulations. Or associate with the manufacturer


Determine the disposal method.


Part III Component/composition information


Substance √ Mixture □


Dangerous component concentration,


% CAS No.


Trifluoroacetic anhydride


99.5%


407-25-0


Part IV first aid measures


Skin contact: Remove contaminated clothing, immediately remove contaminated clothing, with a large amount of fluid


Rinse with water for at least 15 minutes. Seek medical attention.


Eye contact: Immediately lift eyelids and rinse thoroughly with plenty of running water or saline at least


15 minutes. Seek medical attention.


Suction: Quickly leave the scene to fresh air. Keep your airway clear. dyspnea


When giving oxygen. If breathing and heart stop, immediately perform artificial respiration and cardiac massage. it


Doctor.


Ingestion: Gargle with water, drink milk or egg white. Seek medical attention.


Main symptoms and health effects of exposure to this chemical: corrosive. For the eyes, skin,


Mucosa and upper respiratory tract are strongly stimulated. Inhalation can cause laryngeal, bronchospasm, chemical


Pneumonia, pulmonary edema. Contact can cause burning sensation, cough, headache, vomiting, etc.


Advice to rescuers: Do not come into direct contact with harmful substances.


Doctor's special note: If you can't handle it yourself, please see a doctor immediately.


Prompt medical attention and special treatment: oxygen is administered when breathing is difficult. Such as breathing and cardiac arrest


Stop, immediately perform artificial respiration and cardiac massage.


Part V fire control measures


Fire extinguishing method and extinguishing agent: Firefighters must wear filter gas mask (full cover)


Or isolated breathing apparatus, wear a whole body fire protection suit, in the upwind fire. Container as much as possible


Move from the fire to the open space. Spray water to keep the fire container cool until the fire is over. Be on fire


If the container in the field is discolored or produces sound from the safety relief device, it must be evacuated immediately.


Extinguishing with water is ineffective.


Fire extinguishing agent: dry powder, sand. Do not use water or foam to extinguish fires.


Especially dangerous: in case of low alcohols and water chemical reaction and decomposition. For many metals especially tide


The presence of wet air is corrosive.


Special fire extinguishing method: dry powder, sand. Do not use water or foam to extinguish fires.


Protective equipment to protect firefighters: Firefighters must wear filter gas masks (full


Mask) or isolation respirator, wear full body fire protective clothing.


The sixth part leakage emergency treatment


Protective measures, protective equipment and emergency procedures for operators: recommended for emergency personnel


Self-contained respirator, full body suit. Do not contact spills directly. Cut off leakage if possible


Leakage source. Quickly evacuate the contaminated area to the safety zone, and isolation, strict restrictions


In and out. Cut off the fire.


Environmental protection measures: prevent the flow into sewers, flood drains and other restricted Spaces.


Containment and removal methods for leaking chemicals and disposal materials used: Small amounts of leakage: sand


Mix soil, dry lime or soda ash. Large leakage: build a embankment or dig a pit to contain it. Use bubble


Foam cover reduces steam hazards. Transfer by pump to tank car or special collector, recovery or transport


Disposal at waste disposal site.


Preventive measures to prevent secondary hazards: No data available.


Part VII operation, disposal and storage


Operation and disposal: closed operation, provide sufficient local exhaust air. Prevent steam from leaking into the workplace


In the air. Operators must be specially trained and strictly abide by the operating procedures. Suggested operand


The personnel should wear self-priming filter gas mask (full cover), wear adhesive cloth anti-poison jacket and wear rubber


Gloves. Keep away from fire and heat. No smoking in the workplace. Use explosion-proof ventilation systems


And equipment. Welding, cutting and other operations should not be carried out before removing liquid and vapor. Avoid producing


Smoke. Avoid contact with oxidants, acids and alkalis. The container and the transmission device should be grounded


Prevent static electricity. When filling, the flow rate should be controlled, and there is a grounding device to prevent static accumulation. with


Prepare the corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. Empty containers may be


Residual harmful substances.


Storage: Store in a cool, ventilated warehouse. Keep away from fire and heat. Keep out of direct sunlight.


The storage temperature should not exceed 40℃. Keep the container sealed. Should be associated with oxidants, acids, alkalis, food


Store chemicals separately and do not mix them. Explosion-proof lighting and ventilation facilities are adopted. interdict


Use mechanical equipment and tools that generate sparks easily. The storage area should be equipped with leak emergency treatment equipment and synthetics


Suitable containment material.


Part VIII Contact control and personal protection


Occupational exposure limit: No data available.


Monitoring method: No data.


Biological limits: No data available.


Monitoring method: No data.


Engineering control method: closed production process, strengthen ventilation.


Respiratory system protection: When the concentration in the air exceeds the standard, you must wear a self-priming filter gas mask (all


Mask) When rescuing or evacuating in an emergency, you should wear an air respirator.


Hand protection: Wear rubber gloves.


Eye protection: Respiratory system protection has been protected.


Skin and body protection: Wear tape and anti-poison clothing.


Special protective measures: Smoking, eating and drinking are prohibited at the work site. Work done, shower more


Clothes. Maintain good hygiene.


Part IX: Physical and chemical properties


Appearance and properties: colorless smoky liquid


Odor: Pungent odor


pH value: No data available


Melting point/freezing point (℃)


: -63.5


Boiling point, initial boiling point and boiling range (℃) : 39.5-40 flash point (℃)


: No data


Upper explosion limit % (V/V) : No data lower explosion limit


% (V/V) : No data available


Vapor pressure (KPa) : No data vapor density (air


=1) : 3.9


Relative density (water =1) : 1.49


Solubility: Easily soluble in water


Octanol/water partition coefficient: no data spontaneous combustion temperature (℃)


: No data


Decomposition temperature (℃) : No data available


Odor threshold: No data available


Evaporation rate: No data available


Flammability: No data available


Critical temperature (℃) : No data available


Critical pressure (MPa) : No data available


Part X Stability and reactivity


Stability: Stability.


Dangerous reaction: easy to burn, decomposition.


Conditions to be avoided: open flame, high temperature, presence of incompatible substances.


Incompatible substances: strong oxidant, strong alkali, strong acid, water, alcohol, low carbon steel, galvanized steel,


Zinc.


Dangerous decomposition products: carbon monoxide, carbon dioxide, hydrogen fluoride, combustion of organic matter


Other types of pyrolysis products.


Intended use: pharmaceutical, pesticide intermediates.


Predictable wrong use: for food additives.





Acute toxicity: Irritation to the skin. Inhalation is harmful to health.


Skin irritation or corrosion: Irritating to the skin and causing a burning sensation.


Eye irritation or corrosion: Irritation to the eyes.


Respiratory or skin allergies: Contact can cause burning, cough, headache, vomiting, etc.


Germ cell mutation: No data available.


Carcinogenicity: No data available.


Reproductive toxicity: No data available.


Specific target organ system toxicity - single exposure: No data available.


Specific target organ system toxicity - repeated exposure: No data available.


Inhalation hazards: Inhalation can cause laryngeal, bronchospasm, chemical pneumonia, pulmonary edema.


Toxicokinetics, metabolism and distribution information: No data available.


Part XII ecological information


Ecotoxicity: No data available.


Persistence and degradability: No data available.


Potential bioaccumulation: No data available.


Migration in soils: No data available.


Part XIII Waste disposal


Disposal method: Disposal according to the requirements of relevant national and local laws and regulations. Or manufacture with manufacturers


Contact with each other to determine the disposal method.


- Residual waste: disposal in accordance with the requirements of relevant national and local regulations.


Contaminated containers and packaging: disposal in accordance with the requirements of relevant national and local regulations.


Disposal precautions: The operator must wear a filter type gas mask (full cover) or isolation type


Respirator, wear full body fire protective suit.


Part XIV Transport information


United Nations Dangerous Goods Number (UN number) : 3265


United Nations Transport name: Esters, not otherwise specified.


United Nations Risk Classification: 8.


Packing mark: Corrosive liquid.


Packaging Category: I


Packing method: steel-plastic composite drum


Marine pollutants (Yes/No) : No data available.


Transport notes: When railway transport must be reported to the railway Bureau for trial operation, trial operation period is two years. try


After the end of the operation, write a trial operation report, reported to the Ministry of Railways officially announced the transport conditions. Rail time


In strict accordance with the Ministry of Railways "dangerous goods transport Rules" dangerous goods collocation table


Pretend. Transport vehicles should be equipped with the appropriate variety and quantity of fire equipment and leakage emergency


Take care. It is best to transport early and early in summer. The tank (tank) car used in transportation should have a grounding chain and groove


The hole separator can be provided to reduce static electricity generated by vibration. It is strictly prohibited to interact with oxidants, acids, alkalis and food


Mixed with chemicals, etc. During transportation, it should be protected from sunlight, rain and high temperature. stopover


Keep away from fire, heat sources and high temperature areas. The exhaust pipe of the vehicle carrying the article must be equipped with a stop


Fire device, it is prohibited to use mechanical equipment and tools that are easy to produce sparks. For road transport


Follow the prescribed route and do not stay in residential and densely populated areas. It should be banned during rail transport


Stop slipping. It is strictly prohibited to use wooden or cement ships for bulk transport.


Part XV Regulatory information


Regulations on the Safety Administration of Hazardous Chemicals (promulgated by The State Council on January 26, 2002),


Regulations on the Safe Use of Chemicals in the workplace ([1996] Ministry of Labor No. 423) and other regulations are targeted


Relevant regulations have been made for the safe use, production, storage, transportation, loading and unloading of dangerous goods


To be sure; In accordance with the General Rules for the Classification and Risk Publicity of Chemicals (GB 13690-2009)


The quality is classified as corrosive liquid.


Part XVI Other information


Other important information:


Filling time: 2009-11-26


Modification note: Revised according to the preparation of chemical safety technical specifications (GB16483-2008)


Writing.


Reference: General Rules for the Classification and Risk Publicity of Chemicals (GB 13690-2009)